A deadly bomb explosion at a Vegas office building sends Grissom and the CSI team in search of a serial bomber. Their primary suspect is the building's overly helpful security guard, who knows more than he should about blowing things up.
Grissom and Catherine investigate when a leg is found severed from a body in a lake. Meanwhile, Sara and Nick investigate a fraternity pledging gone terribly wrong.
Grissom and Brass track down a serial killer who stages his murders so that they appear to be suicides. Meanwhile, Willows and Brown investigate a robbery and a homicide.
Catherine violates department protocol when she takes the case of a rape accusation against her ex-husband. Meanwhile, Warrick and Sara search for the missing bullet that will either exonerate or indict a cop for murder.
Grissom and his crew handle their highest profile case to date when the city's former chief of detectives is slain execution-style in his house following a wild party.
A couple leaving a restaurant on their anniversary are killed in the street, and their car is stolen. The crime scene is compromised when it rains shortly after the CSIs arrive.
A battered body tells the CSI team a troubling story, and in the course of their investigation, the evidence not only leads them to those responsible for the young man's death, but also reveals surprising information about Grissom's personal life.
When a teenager and her sister are the sole survivors of the gruesome murder of four members of one family in a quiet suburban neighbourhood, Grissom and his entire team investigate the crime.
The CSI team works backwards from the gruesome discovery of a human eyeball to discover that a missing woman has been murdered, and both her husband and teenage daughter have shocking motives to want her dead.
Grissom and Nick investigate the murder of Alex James, a man who led police on a high-speed chase before exiting his vehicle and dropping dead with a wooden stake in his head.