After being banished from Berlin for trying to obtain a travel visa, Barbara (Nina Hoss) finds herself isolated in a secluded East German village during the summer of 1980 where she works at the local medical clinic. Subject to constant supervision and searches by a menacing GDR officer (Rainer Bock, The White Ribbon) and unable to take so much as an evening stroll without looking over her shoulder, she quickly searches for a way to leave the Eastern bloc once and for all. But her yearnings are gradually transformed as she grows closer to the clinic's head doctor, Andre (Ronald Zehrfeld), a gentle loner who's forced to keep tabs on Barbara and whose intentions are never quite clear, though they appear to be good-natured. Their bond is further enhanced by a love of the profession that has them working overtime to care for two troubled patients: a rebellious teenage runaway, Stella (Jasna Fritzi Bauer), and a young man (Jannik Schumann) who attempted suicide for reasons we will learn about later on.